all

The Wake Forest-Pittsburgh Consortium is part of the Armed Forces Institute of Regenerative Medicine (AFIRM), a "multi-institutional, interdisciplinary network working to develop advanced treatment options for our severely wounded servicemen and women." Information on news, clinical trials, research and collaboration opportunities, and research areas at AFIRM are provided on the website.

The mission of the Stem Cells and Regenerative Medicine (STaR) Center at Baylor College of Medicine is to "facilitate stem cell research of all types at Baylor College of Medicine, and the clinical translation of such research into regenerative medicine." Researchers at STaR study both adult and embryonic stem cells and are interested in understanding how stem cells are simulated to regenerate tissues, especially damaged tissue. Information on current research at STaR and training opportunities are included on the website.

The Center for Regenerative Medicine (CReM) is a collaborative effort among scientists at Boston University and the Boston Medical Center. The aim of the Center is to advance stem cell research and regenerative medicine, including a focus on induced pluripotent stem (iPS) cells. Information on research programs, core facilities, educational opportunities, and protocols can be found on the website.

The CIRM (California Institute for Regenerative Medicine) Portal is found on WikiPathways, and highlights pathway content contributed and maintained by the stem cell research community.

The Cedars-Sinai Regenerative Medicine Institute (RMI) works to bring together research faculty and clinicians to explore regenerative medicine through its five major programs: brain, eye, pancreas and liver, blood, and skeletal. Focus at the Institute is generating induced pluripotent stem (iPS) cells from adult human skin samples. Information on research programs, cores, and educational opportunities can be found on the website.

The Stem Cell Program at Children's Hospital Boston works to "explore, understand, and translate the promise of stem cells into effective clinical therapies and treatments." Users can find information on the stem cell program, labs, and research programs at the Stem Cell Program. Additionally, information on adult stem cells, pluripotent stem cells, an FAQ, and glossary are also available on the website.

From the Clinical Tissue Engineering Center (CTEC) website: CTEC is focused on the translation of basic research and innovation into new therapies and products for the advancement of clinical care. CTEC pairs researchers who are working on new materials and scaffolds, new cell sources, processing methods, new measurement tools and new means of intervention, with innovative clinicians who are inspired by the needs and opportunities for the treatment of diseases of the cartilage, bones, muscles, connective tissue and skin. This community of clinicians, scientists and strategic commercial partners is uniquely positioned to leverage the extensive resources generated by our partnering institutions and internationally recognized programs in Biomedical Engineering, the Cleveland Clinic Orthopaedic and Rheumatologic Research Center, and the Center for Stem Cell and Regenerative Medicine.

The Stem Cell and Regenerative Medicine Program at Duke University strives to "bring together scientists and clinical investigators studying stem cells and their remarkable therapeutic potential." Information on current research projects is available on the website, as well as information on educational opportunities.

The EuroStemCell project was launched in March 2010 and helps to unite more than 90 European stem cell and regenerative medicine research labs in a coordinated effort to exchange with the public about their science. The project is a partnership of scientists, clinicians, ethicists, social scientists, and science communicators, and also includes teachers and patient representatives.

The Department of Anatomy and Regenerative Biology is located at The George Washington University and is home to a traditional anatomy department and a modern biomedical research department focusing on molecular, cellular, developmental, and physiological aspects of stem cell and regenerative biology. Information on news and events, seminars, and curriculum is included in the website. Additionally, information on current research projects conducted in the Department is provided.

Stem Cell Biology and Regenerative Medicine at the Gladstone Institutes is located at the University of California-San Francisco. Researchers focus their work using stem cells to understand disease processes and develop new therapies. Information on news and events, seminars, and curriculum is included in the website. Additionally, information on current research projects conducted in the is provided.

From the Stem Cell and Regenerative Biology Department at Harvard University: The Department of Stem Cell and Regenerative Biology (SCRB) is the first cross-school department located in both the Faculty of Arts and Sciences and Harvard Medical School. The Department's focus is the development, maintenance and repair of vertebrate tissues. Emphasis is placed on using these aspects of biology to inform the understanding of human diseases.

From the Institute for Pediatric Regenerative medicine website: The Institute for Pediatric Regenerative Medicine (IPRM) is a collaborative initiative of the UC Davis School of Medicine and the Shriners Hospitals for Children Northern California (SHCNC). The IPRM carries out basic and translational/clinical research, with the aim of helping children with spinal cord dysfunction, orthopaedic disorders and burns. The IPRM occupies more than 27,000 square feet of laboratory space at SHCNC on the UC Davis Medical Center (UCDMC) campus in Sacramento. One focus of the IPRM is on the potential for stem cell-based therapies to facilitate the regeneration of neural and connective tissues and skin. A second research interest of the IPRM is on Immunomodulation in children with burns or spinal cord injuries.

The International Stem Cell Registry is a searchable, comprehensive database that includes published and validated unpublished information on all human embryonic (hESC) and induced pluripotent (iPS) stem cell lines. Information on the registry includes current information on all known human pluripotent cell lines. This also includes cell lines approved by the National Institute of Health (NIH) for federal funding and those that were derived through other public or private funding sources. Non-profit institutions, academic centers, research enterprises, stem cell banks and industry based in the United States and abroad are also included in the registry.

The Institute for Cell Engineering (ICE) at the Johns Hopkins School of Medicine was established to help foster a collaborative environment across the university to understand the basic biology of stem cells, basic cell processes, and apply new ideas to the field of cell engineering. ICE focuses their work on four basic research programs: Immunobiology, Neuroregeneration, Stem Cell Biology, and Vascular Biology. These research programs investigate a wide range of conditions including Parkinson's disease, ALS, diabetes, heart failure, stroke, and spinal cord injury.

The Louis J. Fox Center is a partnership between the University of Pennsylvania Medical Center (UPMC) Eye Center and the McGowan Institute for Regenerative Medicine. Research at the Louis J. Fox Center focuses on the the restoration of sight through tissue regeneration, transplantation, and technology. News, events, and information about research at the Center is provided on the website.

From the Tissue Engineering and Organ Fabrication Lab website: The Tissue Engineering & Organ Fabrication Laboratory at Harvard Medical School works closely with engineers and scientists from MIT and the Draper Laboratories. Collaborating with Professor Robert Langer from MIT, we began building living tissues using living cells on specially designed degradable plastics. This invention is now patented and being tested worldwide. Our work is also a part of the Center for Innovations in Minimally Invasive Therapies as well as the Department of Surgery at the Massachusetts General Hospital.

From The National Academies Press website: Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

The Center for Stem Cell and Regenerative Medicine is located at the National Center for Regenerative Medicine and composed of researchers from Case Western Reserve University, University Hospitals Case Medical Center, The Cleveland Clinic, Athersys, Inc. and Ohio State University. The Center provides a comprehensive and coordinated "bench-to-bedside" approach to regenerative medicine. Research at the Center includes: basic and clinical research programs, biomedical and tissue engineering programs, and development and administration of new therapies to patients.

From the National Human Neural Stem Cell Resource: The National Human Neural Stem Cell Resource provides neural stem cells harvested from the post-natal, post-mortem, human brain or derived from induced pluripotent stem cells to the research community for stem cell research. Several brain scans as well as cultures from normal and genetically mutant specimens are represented in the Resource.

From the Tissue Engineering Program Area at the National Institute of Biomedical Imaging and Bioengineering (NIBIB): This program supports the development of enabling technologies including real-time, non-invasive tools for assessing the function of engineered tissues; real-time assays that monitor the interaction of cells and their environment at the molecular and organelle level; predictive computational models for engineering function 3D tissues; high-throughput assays and instruments to reduce the cost, time, and complexity of tissue engineering; novel bioreactor techniques for expanding stem cells and growing tissues and organs on a large scale; and strategies for preserving, sterilizing, packaging, and transporting living-tissue products. The program also supports applications of rational engineering design principles to functional engineered tissues; the development of novel biomaterials for use as tissue scaffolds that mimic the extracellular matrix and support multiple cell types in defined spatial orientation; and engineering approaches to study how biomaterials interact with cells and guide cell growth, differentiation, and migration.

The Stem Cell Biology Group of the National Institute of Environmental Health Sciences seeks to understand the molecular basis of self-renewal and differentiation in embryotic stem (ES) cells. Information about the research conducted with the Stem Cell Biology Group is provided on the website.

This webpage provides the text for the National Institutes of Health (NIH) Guidelines on Human Stem Cell Research, effective July 7, 2009.

From the Stem Cell Information website: Written by experts in stem cell research, this report describes advances made since 2001 and outlines the expectations for future developments. It discusses current stem cell biology, not limited to NIH-funded research. Authors explain research using cells from embryos, fetal tissue, and adult tissues. The report was originally written in 2006, and NIH is adding new chapters as new areas of scientific research emerge. The entire report may be downloaded free of charge from this page, either as a single PDF file (3 MB) or by chapter (click on a "PDF" link below to download a PDF of that section). You will need a software viewer such as Adobe Reader to view the files.